In recent years, the European circular economy is being shaped, presenting new opportunities and challenges in terms of materials reusing, waste processing, remanufacturing and refurbishing of products. Processing products after their (first) life requires high level of flexibility which is attributed to the different part conditions and variability. The EU-funded ROB4GREEN project will develop user-friendly, collaborative, AI-driven robotic systems capable of adapting to various R-strategies for processing products after their (first) lifecycle. These systems will enhance existing robot skills and generate new ones while operating autonomously. The ROB4GREEN solution will be validated at scale in major industries, showcasing optimisation ranging from the “cell” level to the whole “value chain”, thereby contributing to the goals of the European Green Deal.